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S15.Epimedium (Horny Goat Weed) Extracts.Icariin 10%20%30%50%HPLC.Epimedium brevicornum Maxim Extract.
CAS.RN.NO:489-32-7;.M.F.Molecular Formula: C33 H40 O15.;M.W.Molecular Weight: 674.69;Synonyms:Icariine; -((6-Deoxymannopyranosyl)oxy)-7-(glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
S16.Epimedium (Horny Goat Weed) Extracts.Icariins 20%40%50%HPLC,Flavonoids 10%HPLC.Epimedium brevicornum Maxim Extract.Branches and Leaves
Botanical Source:Epimedium brevicornum Maxim.;Epimedium sagittatum (Siebold. et Zucc.) Maxim., Epimedium koreanum Nakai.,Epimedium pubescens Maxim.,Epimedium sinense, Epimedium wushanense T.S.Ying. This herb is the dried leaf of Epimedium brevicornum Maxim.;Epimedium sagittatum (Siebold. et Zucc.) Maxim., Epimedium koreanum Nakai.,Epimedium pubescens Maxim.,Epimedium sinense, Epimedium wushanense T.S.Ying.,of the barberry family (Berberidaceae).
Common Names&Synonyms:Shorthorned Epimedium Herb extracts; Epimedium segittatum (Sitb.et Zucc.) Maxim extracts;Horny Goat Weed,Lusty goat herb,xianlingpi,
Plant Part Used: Branches and Leaves of Epimedium brevicornum Maxim.
Extract Solubility:soluble in water and ethanol. soluble excelent in alcoholic drink.
Phytochemicals and Constituents of Herba Epimedii:
Main Content: icariin. C33 H40 O15.
Synonyms:Icariine; -((6-Deoxymannopyranosyl)oxy)-7-(glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
Formula: C33 H40 O15. Molecular Weight: 674.69 CAS RN:489-32-7
Chemical Name:3-((6-deoxymannopyranosyl)oxy)-7-(glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
CAS Type 1 Name:4H-1-Benzopyran-4-one, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-
Other Content
All Epimedium herb contains ceryl alcohol;hentriacontane;phytosterol;palmitic acid;stearic acid;oleic acid;linoleic acid; linolenic acid; bilobanol; magnoflorin;glucose;fructose;etc.
Epimedium brevicornum Maxim. contains:baohuosideⅠ(baohuoside I);baohuosideⅡ(baohuosid II);2''-O-rhamnosylicalisideⅡ(2''-O-rhamnosylicaliside II);Sagittatoside B;ikarisoside F;ikarisoside C;icarisideⅠ(icariside I);icarisideⅡ(icariside II);epimedoside A;de-O-methyl-icariin.
Epimedium sagittatum (Sieb. et Zucc) Maxim. contains: icariside; isoquercetin;icaritin-3-O-alfa-rhamnoside; hyperoside; sagittatoside A; sagittatoside B;sagittatoside C; sagittatin A;sagittatin B;anhydroicaritin-3-O-alfa-rhamnoside; icariside B9,icariside D3,icariside E6,icariside E7,icariside H1; icariols A1,icariols A2; sagittin; Beta-sitosterol; Beta-sitosterolglucoside.
Epimedium koreanum Nakai. contains: liquiritigenin; tricin; quercetin; isoliquiritigenin; luteolin; hyperoside;maltol; salidroside;P-hydroxybenzoic acid; daucosterol; emodin; icarisideⅠ(icariside I);icariside Ⅱ(icarisid II);icariside A1; 2"-O-L-rhamnopyranosylicarisidⅡ;epimdeoside;sagittatoside A,sagittatoside B;3,5,7-trihydroxyl-4''-methoxyl-8-prenyl-flavone-3-O-alfa-L-rhalnnopyranside; ikarisoside F; diphylloside A; baohuosideⅡ(baohuosid II); kaempferol-3-O-Beta-D-galactoside A;epimedoside C;baohuosideⅠ(baohuoside I);epimedin A,epimedin B,epimedin C; epimedokoreanosideⅠ(epimedokoreanoside I),epimedokoreanosideⅡ(epimedokoreanoside II); epimedoside A; ikarisoside A; 4''-methoxy-5-hydroxy-8-3,3-dimethylallylflavone-3-glucosyl(1→2)''rhamnn-oside-7-glucoside; 4''-methyoxy-5-hydroxy-8-3,3-dimethyiallyflavone-3-xylosyi(1→2)rhamnoside-7-glucoside;4-methoxy-5-hydroxy-8-3,3-dimethylallylflavone-3-rhamnosyl(1→2)rhamnoside-7glucoside; proanthocyanidin(catechin-(4alfa→8)-epciate-chin(4Beta→8)-catechin); 4-O-methyl-8-r,r-dimethylallyl kaempferol-7-O-D-glucopyranoside; chlorogenic acid;etc.
Epimedium pubescens Maxim. contains:baohuoside Ⅵ(baohuoside VI);hyperoside; rouhuoside,etc.
Epimedium platyetalum K. Meyer. contains:Maohuoside A(3,5-dihydroxy-4′-methoxy-8-(3″-hydroxyisopentyl)-flavone-7-O-β-D-glucopyranoside); and Maohuoside B(5-hydroxy-4′-methoxy-8-prenyl-flavone-3-O-β-D-glucopyranosyl(1→4)-O-α-L-rhamnopyranosyl-7-O-β-D-glucopyranoside, 2); icariin,baohuosideⅠ(baohuosid I); daucosterol, etc.
Product Specification/Models Specifications and Supplying Conditions:
Description: Epimedium P.E.,Horny Goat Weed,Icariins,icariin,AChE Inhibitor.
Plant Part Used: Branches and Leaves
Content Standardized: Icariin 20%.25%.30%.40%.50%80%~95%HPLC Icariins 20%.35%.40%.50%HPLC
Serie Code: S015.S016.
Expiration Date: 18~24Months in Good Condition
Storage Stock: Bulk in Stock
Pricing Terms: C&F;CIF;DDU;DDP.
Delivery Arrange: Soonest on the Day Confirmed
Appearance Showing: Light Pale Yellow Fine Powder
Extracts State: Fine Crystal Powder
Mesh Size: 100% Pass 80 Mesh Screen
Color: Light Yellow Brown to Light Pale Yellow
Odor and Smell: Charateristics
Taste Sense: Flavour with Characteristics
Bulk Density: 0.50g/ml.
Application Mechanism study:the therapeutic action of icariin on erectile dysfunction(ED):
Some clinical researchers do research and showed PDE5 was isolated from the human platelet and PDE4 from the rat liver tissue using the FPLC system (Pharmacia, Milton Keynes, UK) and the Mono Q column. The inhibitory effects of icariin on PDE5 and PDE4 activities were investigated by the two-step radioisotope procedure with [(3)H]-cGMP/[(3)H]-cAMP. Papaverine served as the control drug.
Icariin and papaverine showed dose-dependent inhibitory effects on PDE5 and PDE4 activities. The IC(50) of Icariin and papaverine on PDE5 were 0.432 micromol/L and 0.680 micromol/L, respectively and those on PDE4, 73.50 micromol/L and 3.07 micromol/L, respectively. The potencies of selectivity of icariin and papaverine on PDE5 (PDE4/PDE5 of IC(50)) were 167.67 times and 4.54 times, respectively.
Icariin is a cGMP-specific PDE5 inhibitor that may be developed into an oral effective agent for the treatment of ED.
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