Product Description
Tomato Extract.Lycopene 3%~50%HPLC.

CAS.RN.NO:502-65-8;.M.F.Molecular Formula:C40 H56.Synonyms:-carotene, all-trans lycopene, lycopersicon, solanorubin,Rhodopurpurin. Chemical name.

Botanical Source:Tomato paste,tomato extract,tomato paste extract,tomato extract powder, tomato paste extract crystal.

........Common Names&Synonyms:carotene, all-trans lycopene, lycopersicon, solanorubin, tomato,Rhodopurpurin,Lycopene oil-resin,Lycopene crystals.


Lycopene - A Scientific Overview:

Although lycopene was first isolated in 1873, it is only in the last decade that it has become widely recognized as a potent antioxidant and a potential protector against the risk of certain types of cancer and cardiovascular diseases. Even though the science is still emerging and little intervention data is available, consumer interest in lycopene is growing.

Food Sources:The major food sources of lycopene are tomato-based products. Other good sources are watermelon, guava, papaya, apricots, pink grapefruit and blood oranges. However, 85% of dietary intake of lycopene comes from tomatoes and tomato products.

Chemical name: (all-E)-2,6,10,14,19,23,27,31-Octamethyl-2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecane , -Carotene
Synonyms:-carotene, all-trans lycopene, lycopersicon, solanorubin, tomato,Rhodopurpurin.
Botanical source: Lycopene is kind of natural pigment with bright red color ,it is narrowly distributed world ,it is mainly existed in tomato ,watermelon ,red grapefruit ,Chinese quava ,guava ,balsam pear etc.
Appearance:Park Red Powder.
Specification: Lycopene oil-resin,Lycopene crystals.
Functions:
It is powerful antioxidant ,more than vitamin-E one hundred times and more than b-carotene twice ,it has many biological activies, can stand over entlity ,strengthen immune function ,better for human''s nutrition and health
Applications:For superior physiology function and preventing cancer ,lycopene is called as "new pet of health protection in 21century" it has widely applied in the fields of medicines ,health protection profession and color matching etc


Reference Link: Click for more Details



Mechanism of Action:How does it work?

Non-antioxidant mechanisms have also been proposed. Failure of cell signaling may be a cause of cell overgrowth and eventually cancer. Lycopene may stimulate gap junction communication between cells. It is speculated that lycopene may suppress carcinogen-induced phosphorylation of regulatory proteins such as p53 and Rb antioncogenes and stop cell division at the G0-G1 cell cycle phase. One researcher has hypothesized that lycopene-induced modulation of the liver metabolizing enzyme cytochrome P450 2E1 may be the underlying mechanism of protection against carcinogen-induced preneoplastic lesions in the rat liver. Lycopene may also reduce cellular proliferation induced by insulin-like growth factors. There is some preliminary in vitro evidence for the latter proposal.
The mechanism of the possible antiatherogenic activity of lycopene is likewise unclear. Lycopene''s antioxidant activity is a possibility. Lycopene has also been found to inhibit cholesterol synthesis, to inhibit HMG-CoA (hydroxymethylglutaryl coenzyme A) reductase activity and to upregulate LDL receptor activity in macrophages. A small preliminary study in humans, reported an LDL-cholesterol-lowering effect of lycopene.


How does it work?

Carotenoids work to protect against cancer and aging-related diseases by acting as an antioxidant to counteract damaging effects of free radicals in tissues. Lycopene is one of the major carotenoids found in human blood and tissues, and is found primarily in the testis, adrenal glands, liver, prostate, breast, colon, and lung. Because lycopene cannot be metabolized to Vitamin A, its biological effects in humans have been attributed to other mechanisms. Lycopene is currently considered one of the most efficient carotenoids at protecting against free radicals that damage critical parts of the cell, including lipids, membrane lipoproteins, proteins, and DNA
Lycopene is a red pigment found in plants and is part of a large class of plant compounds called carotenoids. Carotenoids are fat soluble and create yellow, orange or red colors in plants. Carotenoids are not made by humans. Lycopene is not found in high amounts in many plants. The greatest sources of lycopene in fresh fruits and vegetables are watermelon, tomato, red grapefruit and guava.
The red color found in strawberries, cherries, etc. is a water soluble pigment called anthocyanin, and is formed by a very different pathway from the carotenoids.

The primary role of carotenoids in plants is to neutralize compounds created during photosynthesis. These compounds are often hydrogen peroxide or singlet oxygen, both of which will attack and destroy cell membranes, ultimately damaging the cell. Singlet oxygen is oxygen with a higher energy charge because outer orbital electrons are spinning in opposite directions.
Humans breathe in oxygen as O2. The biological processes in the body use oxygen for reactions, frequently creating singlet oxygen as a byproduct. The singlet oxygen is very reactive (high electric charge) and therefore must be eliminated by the body before cell damage occurs. The body uses antioxidants, compounds that look for singlet oxygen and neutralizes it. Of the carotenoids, lycopene is the most effective oxygen scavenger because it can neutralize several singlet oxygen with one lycopene molecule. Other antioxidants are Vitamin C (ascorbic acid) and Vitamin E.


Reference Link: Click for more Details


Lycopene Brief Benefit and Common Knowledge:

Lycopene, a carotene carotenoid, is the most effective quencher of singlet oxygen free radicals yet discovered.
Lycopene quenches singlet oxygen free radicals 2 times more effectively than Beta-Carotene and 100 times more effectively than Vitamin E.
Lycopene retards the damage caused by oxidized LDL Cholesterol.
Lycopene protects against many of the toxic effects of Radioactivity.
People infected with HIV (the underlying cause of Acquired Immune Deficiency Syndrome (AIDS)) are generally deficient in Lycopene (indicating that supplemental Lycopene may be of benefit to HIV-positive persons) [epidemiological evidence].
Lycopene inhibits the proliferation of cancer Cells involved in Breast cancer .
Lycopene protects against Cervix (cervical) cancer [women with high serum
Lycopene levels have 80% less risk of developing cervical cancer than those with low serum Lycopene levels].
Lycopene protects against Colon cancer [epidemiological evidence].
Lycopene inhibits the proliferation of cancer Cells involved in Endometrial cancer.
Lycopene protects against Esophagus (esophageal) cancer [epidemiological evidence].
Lycopene protects against Liver cancer [research - animals].

Lycopene inhibits the proliferation of cancer Cells involved in Lung cancer .
Lycopene protects against Mouth cancer (oral cancer) [epidemiological evidence].
Lycopene protects against Pancreatic cancer [persons with the lowest levels of serum Lycopene have a 500% greater risk of developing Pancreatic cancer than those who consume higher amounts of Lycopene].
Lycopene protects against Pharynx (pharyngeal) cancer [epidemiological evidence].
Lycopene reduces the risk of Prostate cancer [research and epidemiological studies support the role of Lycopene in the prevention of Prostate cancer ].
Lycopene protects against Stomach cancer [epidemiological evidence].
Lycopene lowers LDL Cholesterol levels [60 mg of Lycopene per day for 3 months caused a reduction in LDL Cholesterol of an average of 14%].
Lycopene may help to prevent Alzheimer''s Disease [epidemiological evidence: persons who consume higher levels of Lycopene have a lower incidence of Alzheimer''s Disease].
Lycopene is the predominant Carotenoid that concentrates in the Testicles.
Lycopene is an open-chain unsaturated carotenoid that imparts red colour to tomatoes, guava, rosehip, watermelon and pink grapefruit.
Lycopene is a proven antioxidant. Antioxidants neutralize free radicals, which may damage the body''s cells.
Research shows that lycopene in tomatoes can be absorbed more efficiently by the body if processed into juice, sauce, paste and ketchup. The chemical form of lycopene found in tomatoes is converted by the temperature changes involved in processing to make it more easily absorbed by the body.
In the body, lycopene is deposited in the liver, lungs, prostate gland, colon and skin. Its concentration in body tissues tends to be higher than all other carotenoids.
Regular high consumption of fruits and vegetables is recommended as part of healthy eating. Epidemiological studies have shown that high intake of lycopene-containing vegetables is inversely associated with the incidence of certain types of cancer. For example, habitual intake of tomato products has been inversely associated with the risk of cancer of the digestive tract among Italians.In one six-year study by Harvard Medical School and Harvard School of Public Health, the diets of more than 47,000 men were studied. Of 46 fruits and vegetables evaluated, only the tomato products (which contain large quantities of lycopene) showed a measurable relationship to reduce prostate cancer risk. As consumption of tomato products increased, levels of lycopene in the blood increased, and the risk for prostate cancer decreased. The study also showed that the heat processing of tomatoes and tomato products increases lycopene''s bioavailability.
Ongoing preliminary research suggests that lycopene is associated with reduced risk of macular degenerative disease, serum lipid oxidation and cancers of the lung, bladder, cervix and skin.


Reference Link: Click for more Details


Product Specifications and Supplying Conditions:

Tomato Paste Extracts. Lycopene
Description: Tomato Paste Extracts.
Plant Part Used: Tomato Paste.
Specification: Lycopene 3%,6%,12%,25%HPLC.
Serie Code: S-047
Expiration Date: 18~24Months in Good Condition
Storage Stock: Bulk in Stock
Pricing Terms: C&F;CIF;DDU;DDP.
Delivery Arrange: Soonest on the Day Confirmed

Appearance Showing: Red Brown Fine Powder
Extracts State: Fine Crystal Powder
Mesh Size: 100% Pass 80 Mesh Screen
Color: Red Brown
Odor and Smell: Characteristics
Taste Sense: Sweet
Bulk Density: 0.48~0.50g/ml.


Reference Link: Click for more Details

Payment
tt

Delivery
soon

Origin
China

Minimum Order
1kilos

Packaging
25kilo drums

Inspection
HPLC

Samples
Free

Sample Price
US$0