Product Description
Schizandra Berry Extract. Fructus Schisandrae Schizandra Chinensis Extract;Schisandra sphenanthera Extract.EINECS:N/ACAS:223748-53-6 Dried Fruit Schisandrins 1%~9%HPLC.9%UV.Schizandrin A (Deoxyschisandrin) 1% 2% 3%HPLC Schizandrin B (Deoxygomisin A)1% 2%HPLC

Product Feature
As far back as 2697 B.C. Schisandra was classified as superior by Pen-Tsao in the classic Yellow Emperor's Study of Inner Medicine, an encyclopedia of healing plants. In Beng Cao Cang Mu, a great book on pharmacy written by Li Schizheng in the 16th century, schisandra is listed in the highest ranks. It is said to increase energy, replenish and nourish the viscera (internal abdominal organs such as intestines, lungs etc.), improve vision, boost muscular activity and sooth both coughs and disgestive upsets.

One of the primary medicinal agents of Chinese herbal medicine since antiquity. The first recorded use of schisandra is found in China's earliest text of herbal medicine, the Divine Husbandman's Classic of the Materia Medica, which is believed to have originated in the first century B.C. In it, schisandra is said to "prolong the years of life without aging," and it is also said to increase energy (called "qi," pronounced "chee"), suppress cough, treat fatigue, and act as a sexual tonic in men.

The classical treatise on Chinese herbal medicine, the Shen Nung Pen Tsao Ching, describes schisandra as a high-grade herbal drug useful for a wide variety of medical conditions~especially as a kidney tonic and lung astringent. In addition, other textbooks on traditional Chinese medicine note that schisandra is useful for coughs, night sweats, insomnia, thirst, and physical exhaustion.

Our exclusive Freshcare System inhibits normal plant oxidation, maintaining product potency and extending freshness. It includes all-natural antioxidants in each capsule, oxygen-absorbing packets in each bottle, special air-tight seals and amber glass packaging for uncompromised quality.

Schisandra has long been used in the traditional medicines of Russia and China for a wide variety of conditions including asthma, coughs, and other respiratory ailments, diarrhea, insomnia, impotence, and kidney problems. Hunters and athletes have used schisandra to increase endurance and combat fatigue under physical stress.

In Traditional Chinese Medicine, schisandra berries have been used predominantly for the lungs and kidneys as an astringent tonic to arrest mucous discharges, alleviate spontaneous sweating, and check urinary and reproductive secretions such as in urinary incontinence and spermatorrhea, an involuntary loss of semen.

Schisandra is a famous tonic historically consumed by Chinese royalty and by Daoist masters. It is one of the few herbs that contains all three treasures. Schisandra is renowned as a beauty tonic and is considered to be a youth preserving herb. It has been used for centuries to make the skin soft, moist and radiant. It is also said to be a powerful tonic to the brain and mind, and is believed in China to improve memory. It is also said to be an excellent sexual tonic when consumed regularly. It is said to help produce abundant sexual fluids, increase sexual endurance and to strengthen the whole body. It is used in many tonic formulations as an "astringent." Schisandra has a wonderful multi-layered flavor when processed properly.

Product Specification/Models
Specifications and Supplying Conditions:

Schisandra Fruit P.E. Schisandrins1%,2%HPLC

Description: Schisandra Fruit P.E.
Plant Part Used: Dried Fruit
Content Standardized: Schisandrins1%,2%HPLC
Serie Code: S-031
Expiration Date: 18~24Months in Good Condition
Storage Stock: Bulk in Stock
Pricing Terms: C&F;CIF;DDU;DDP.
Delivery Arrange: Soonest on the Day Confirmed

Appearance Showing: Yellow Brown Fine Powder
Extracts State: Fine Crystal Powder
Mesh Size: 100% Pass 80 Mesh Screen
Color: Yellow Brown
Odor and Smell: Charateristics Aromatic
Taste Sense: Flavour with Characteristics,light bitter.
Bulk Density: 0.48g/ml.

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Application
Common Uses and Research Application of Schisandra related products:

More recently, the focus of schisandra research has been on its use in treating diabetes mellitus. Additionally, a protective effect on cardiovascular tissue insulted with chemical agents or ischemia has also been shown in vivo. As well, anti-inflammatory activity has been reported in in vitro, animal models, and clinical studies.

1.General Tonic: Schisandra is a major tonic herb and acts throughout the body, strengthening and toning many different organs.

2.Sexual stimulant: Probably best known as a sexual tonic for both men and women, schisandra reputedly increases the secretion of sexual fluids and, in men, it also improves sexual stamina.
Treats seminal emission and spermatorrhoea due to lack of consolidation of the essence gate as a result of deficiency of the kidneys:
The herb can nourish the kidneys to astringe seminal emission. It can be used together with mantis ovum, Cherokee rose fruit (Fructus Rosae Laevigatae), fossil fragments, etc.
Schisandra is considered to have "aphrodisiac" qualities, especially when combined with other Kidney tonics. Furthermore, Schisandra is one of the most important astringent herbs used in Chinese herbalism. An astringent herb conserves fluids, and in the case of Schisandra, it tends to contain sexual fluids until the appropriate time of release. Thus, consuming Schisandra for a period of time, one tends to build up sexual fluids. Schisandra is used in sexual formulations to prevent premature ejaculation and to help promote incredible endurance.


3.Female elixir Booster: Schisandra is said to increase the Water Qi in the Kidney. In particular, it is said to vastly increase the "water of the genital organs," referring to the sexual fluids. Schisandra is said to promote the production of semen. It is famous for its ability to relieve sexual fatigue and for increasing the sexual staying-power in men. Schisandra is also said to increase circulation in and sensitivity of the female genitals. Many women claim increased genital warmth and sensation after using Schisandra for a period of time. The Chinese sexual classics claim that continuous use by a woman will increase the amount of "female elixir," a euphemism for vaginal secretions, during intercourse.


4.Liver treatment herb: Schisandra has proven benefits for the liver, and is used in the treatment of hepatitis and poor liver function.
Research into schisandra has focused largely on the lignans, which have a pronounced anti- hepatotoxic (liver-protective) action. Up to 30 different lignans have been identified in schisandra, which all contribute to this effect. Research from 1972 onward has reported the beneficial action of schisandra on the liver, and one clinical trial indicated a 76% success rate in treating patients with hepatitis, with no side effects being noted.

5.Generates vitality: Schisandra develops the primary energies of life, and generates vitality and radiant beauty when used regularly for some time. If used for 100 days successively, Schisandra is said to purify the blood, sharpen the mind, improve memory, rejuvenate the Kidney energy (especially the sexual functions in both men and women), and cause the skin to become radiantly beautiful.

6.Sedative: Although a stimulant, schisandra is used in Chinese medicine to "quiet the spirit and calm the heart." It is given for insomnia and dream disturbed sleep, and is a fine example of how adaptogenic herbs often work in apparently contradictory ways to restore normal body function.

7.Mental & emotional remedy: In China, schisandra berries have traditionally been prescribed to treat mental illnesses such as neuroses. They are also given to improve concentration and coordination, and are a traditional remedy for forgetfulness and irritability. Schisandra''s effectiveness for treating these problems has now been borne out by research.


8.Respiratory infections: Schisandra is used in the treatment of respiratory infections such as chronic coughs, shortness of breath, and wheezing.

Treats prolonged coughing and dyspnea (difficult breathing) of the deficiency type:
Astringing with its sour flavor and moistening with its warm nature, this herb can astringe lung-qi in the upper part of the body and nourish kidney-yin in the lower part, so it is indicated for prolonged coughing due to deficiency of the lungs and dyspnea and coughing due to deficiency of both the lungs and the kidneys.
a) Prolonged coughing due to deficiency of the lungs:
This herb is often used together with poppy shell (Pericarpium Papaveris), e.g., Wuweizi Wan.
b) Dyspnea and coughing due to deficiency of both the lungs and the kidneys:
This herb is often used together with medicinal cornel fruit (Fructus Corni), prepared rehmannia, yam, etc., e.g., Duqi Wan.
c) Dyspnea and coughing due to fluid retention of the cold type:
This herb can also be used together with ephedra, wild ginger (Herba Asari), dried ginger, etc., which are ventilating and dispersing with their pungent taste and warm nature.

9.Balancing fluid levels: Schisandra is used to tone up and strengthen kidney function and to help the body to balance levels of fluid, making it helpful for treating night sweats, thirst, and urinary frequency.
Fluid imbalance. Because of its kidney tonic effect, schisandra is useful in treating thirst, night sweats, excessive sweating, urinary incontinence, and the frequent urge to urinate.
Sour and sweet in taste, this herb can replenish qi, promote the production of body fluid and quench thirst.
a) Hyperhidrosis (excessive sweating) and thirst due to impairment of qi and yin by heat:
This herb is often used together with ginseng and ophiopogon root, e.g., Shengmai San.
b) Diabetes with thirst and polydipsia (excessive or abnormal thirst) due to yin deficiency and intense internal heat:
This herb is mostly used together with herbs that replenish qi and promote the production of body fluid, such as yam, windweed rhizome (Rhizoma Anemarrhenae), Chinese trichosanthes root (Radix Trichosanthis), milk vetch root (Radix Astragali seu Hedysari), etc., e.g., Yuye Tang.


10.Treats prolonged and incessant diarrhea due to deficiency-cold of the spleen:
This herb can also astringe the intestines to arrest diarrhea. It is often used together with malaytea scurfpea fruit (Fructus Psoraleae), evodia fruit, nutmeg, etc., e.g., Sishen Wan.

11.Treats palpitations, insomnia and dreaminess:
This herb can not only nourish and replenish the heart and kidneys, but also relieve mental stress. Therefore it is indicated for palpitations, insomnia, dreaminess, etc., due to emotional distress as a result of loss of yin and blood. In addition, it can be selected for use by those suffering from insomnia owing to any other cause.
It is often used together with raw rehmannia, red-rooted salvia root (Radix Salviae Miltiorrhizae), wild jujube seed (Semen Ziziphi Spinosae), etc.


12.Nervous system: Schisandra is known to stimulate the nervous system, increasing the speed of reflex nervous responses and improving mental clarity. The berries are thought to be potentially useful in the treatment of depression, and are known to help improve irritability and forgetfulness.
This herb is considered to be one of the premium mind tonics of herbalism. It is used to sharpen concentration, improve memory and increase alertness. Yet, unlike caffeine-like stimulants, Schizandra does not produce nervousness. In fact, some people consider Schisandra mildly "calming" while producing wakefulness and improved focus.
It has been demonstrated that human intellectual activity can be enhanced and work efficiency increased by consuming Schisandra. Various tests have shown that moderate therapeutic doses of Schizandra can improve various activities requiring concentration, fine coordination, sensitivity and endurance. The tests in humans confirming Schisandra''s efficacy in these areas range from threading needles to running marathons.


13.Uterus: Schisandra stimulates the uterus, strengthening rhythmic contractions.

14.Adaptogenic herb: Research has shown that in common with ginseng, schisandra has adaptogenic properties, helping the body to adapt to stress

15.Treats spontaneous perspiration and night sweat: This herb can astringe the lungs to arrest sweating.It can be used together with ephedra root, oyster shell, etc.

16.Skin rashes: Recently,Chinese herbalists have started to use schisandra to treat urticaria (hives) and other skin problems, including eczema. It is usually given for these conditions in the form of a medicinal wine.

17.Skin Beautify: Schisandra is widely used to beautify the skin and to protect the skin from the damaging effects of the sun and wind. Due to the astringent quality of Schisandra, the skin tends to hold its moisture and becomes full and beautiful. It has always been very popular with the wealthy men and women of China because of its youth preserving and rejuvenating effects. I have seen the benefits of this herb with my own eyes hundreds of times in my life. People who start taking Schisandra regularly all change for the better. Their skin virtually glows and becomes clear and fine after several months.
For use as a general tonic in China, patients are advised to chew dried schisandra berries daily for 100 days. Skin conditions are usually treated with a medicinal wine formulation.


18.Improve Vision: Human studies have also shown that Schisandra can improve vision, even enlarging the field of vision, and can improve hearing. It also improves the discrimination ability of the skin receptors. It has been determined that this increased sensitivity is due to improved function of the central nervous system''s ability to analyze data flowing to it from the peripheral sensors.
Eyesight Difficulties:So-called night blindness could be corrected with the use of schisandra. Adaption to darkness was improved. There was a general increased sharpness of vision and a widening of the boundaries of the field of vision after a 10-day course of use of schisandra.

19.Circulatory disorders: Schisandra may be used to treat poor circulation and poor heart function.

20.Fatigue: Schisandra may help to reduce fatigue, improve endurance, improve work performance, and build strength. It is recommended for persons who need high levels of energy, such as athletes.

21.Sensory organ failure: Schisandra has been used to help improve failing sight and hearing. It enhances the sensation of touch.

22.Neurasthenic Disorders: Patients with neurasthenic problems were given the schisandra berries and showed a significant improvement in general well-being. Headaches disappeared. Sleep normalized. Appetite improved. Symptoms disappeared completely after the 25th to 27th day. Thereafter, the syndromes of fatigue and exhaustion diminished more rapidly. There was an improvement in mental and physical performance.


23.Chronic Gastritis: Patients who suffered from chronic gastritis or thrombocystopenia were given the schisandra berries. There was a balancing of the levels of acidity in the stomach and the intestinal functions were soothed. In hypoacidic gastritis, a two to three week intake of the schisandra berries brought about a stable improvement.

24.Additional uses: Schisandra is used for a wide variety of other physical disorders, including diarrhea and dysentery, as well as to help improve failing sight and hearing.

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Other Information
How much is usually taken?Suggestions of Schisandra.
Use of schisandra fruit ranges from 1.5-15 grams per day. The tincture, in the amount of 2-4 ml three times per day, can also be used.

Are there any side effects or interactions? Side effects involving schisandra are uncommon but may include abdominal upset, decreased appetite, and skin rash.

Certain medications may interact with schisandra. Refer to the drug interactions summary for a list of those medications. It is recommended you discuss the use of schisandra and your current medication(s) with your doctor or pharmacist.

Within Healthnotes Online, information about the effects of a particular supplement or herb on a particular condition has been qualified in terms of the methodology or source of supporting data (for example: clinical, double blind, meta-analysis, or traditional use). For the convenience of the reader, the information in the table listing the supplements for particular conditions is also categorized. The criteria for the categorizations are: Primary indicates there are reliable and relatively consistent scientific data showing a health benefit. Secondary indicates there are conflicting, insufficient, or only preliminary studies suggesting a health benefit or that the health benefit is minimal.Other indicates that an herb is primarily supported by traditional use or that the herb or supplement has little scientific support and/or minimal proven health benefit.


Safety and Acute toxicity:

Schizandrin A:

Chemical Name: Dibenzo(a,c)cyclooctene,5,6,7,8-tetrahydro-6,7-dimethyl-1,2,3,10,11,12-hexame thoxy
CAS: 61281-38-7.Molecular Formula: C24-H32-O6.Weight: 416.56
Synonyms: Deoxyschisandrin

Acute toxicity(LD50): LDLo-lowest published lethal dose. Intraperitoneal. Rodent-mouse. 1gm/kg
Toxic Effects: Behavioral-altered sleep time(including change in righting reflex)
Reference: CMJODS Chinese Medical Journal(Beijing,English Edition).(China International Book Trading Corp., POB 2820,Beijing. Peop,Rep.China) V.1-1975- Adopted vol.no.92 in 1979. Volume(issue)/page/year: 93,41,1980.

Schizandrin B:

Chemical Name:Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole,5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-,stereoisomer
CAS No:61281-37-6; 64121-95-5.Molecular Formula:C23-H28-O6.Molecular Weight: 400.51
Synonyms:Deoxygomisin A,Gamma-schisandrin;Schisandrin B; gamma-Schizandrin;Schizandrin B;Wuweizisu B.

Acute toxicity(LD50):LD50-Lethal dose,50 percent kill. Intraperitoneal. Rodent-mouse, 2gm/kg.
Toxic Effects:Behavioral-altered sleep time (including change in righting reflex)
Reference: CMJODS Chinese Medical Journal (Beijing,English Edition).(China International Book Trading Corp., POB 2820,Beijing. Peop,Rep.China) V.1-1975- Adopted vol.no.92 in 1979. Volume(issue)/page/year: 93,41,1980.

Schizandrol A:

Chemical Name:Benzo(a,c)cycloocten-6-ol,5,6,7,8-tetrahydro-6,7-dimethyl-1,2,3,10,11,12-hexamethoxy-,stereoisomer
CAS No.:7432-28-2.Molecular Formula: C24-H32-O7.Molecular Weight: 432.56.
Synonyms:Schisandrin;Schizandrin; Schisandrol A;Schizandrol A; Wuweizi alcohol A;Wuweizichun A

Acute toxicity(LD50):
LD50-lethal dose,50 percent kill. Oral.Rodent-mouse: 1448mg/kg.
Toxic Effects:Autonomic Nervous System-smooth muscle relaxant(mechanism undefined,spasmolytic)
Lungs,Thorax,or Respiration-other changes.
Nutritional and Gross Metabolic-body temperature decrease.

LD50-Lethal dose,50 percent kill. Intraperitoneal.Rodent-mouse. 518mg/kg
Toxic Effects:Autonomic Nervous System-smooth muscle relaxant(mechanism undefined,spasmolytic)
Lungs,Thorax,or Respiration-other changes.
Nutritional and Gross Metabolic-body temperature decrease.

LD50-Lethal dose,50 percent kill.Subcutaneous.Rodent-mouse.1861mg/kg.
Toxic Effects:Behavioral-sleep.
Behavioral-somnolence (general depressed activity)
Nutritional and Gross Metabolic-body temperature decrease.
Reference: Journal of Pharmacy.No.1-1981-Volume (issue)/page/year: 101,1030,1981.

Gomisin A(Schizandrol B):

Chemical Name: Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-6-ol,5,6,7,8-tetrahydro-6,7-dimethyl-1,2,3,13-tetramethoxy-,stereoisomer
CAS No.: 58546-54-6; 61281-39-8.Molecular Formula: C23-H28-O7.Molecular Weight: 416.51
Synonyms:Gomisin A; Schisandrol B;Schizandrol B;Wuweizi alcohol B;Wuweizichun B.

Acute toxicity(LD50):
LD50-Lethal dose,50 percent kill. Oral. Rodent-mouse. 777mg/kg.
Toxic Effects:Behavioral-sleep
Behavioral-somnolence (general depressed activity)
Nutritional and Gross Metabolic-body temperature decrease.

LD50-Lethal dose,50 percent kill. Intraperitoneal.Rodent-mouse. 390mg/kg.
Toxic Effects:Behavioral-sleep
Behavioral-somnolence (general depressed activity)
Nutritional and Gross Metabolic-body temperature decrease

LD50-Lethal dose,50 percent kill. Subcutaneous.Rodent-mouse,500mg/kg.
Toxic Effects:Behavioral-sleep
Behavioral-somnolence (general depressed activity)
Nutritional and Gross Metabolic-body temperature decrease.
Reference:Journal of Pharmacy.No.1-1981-Volume (issue)/page/year: 101,1030,1981.

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Origin
China

Minimum Order
1kgs

Packaging
25kgs/drum

Inspection
HPLC

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